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Please use this identifier to cite or link to this item: https://repository.uksw.edu/handle/123456789/22359
Title: Prevalensi Gout Arthritis di Desa Kaweruan dan Analisis Pohon Keluarga Penderita Gout Arthritis di Desa Batu Kabupaten Minahasa Utara
Authors: Tewu, Virgin Febrianti
Keywords: gout arthritis;analisis predigree;Minahasa Utara
Issue Date: 10-Dec-2021
Abstract: Gout arthritis (GA) adalah penyakit artritis inflamatif utamanya di persendian akibat pembentukan kristal monosodium urate (MSU) dalam jaringan yang pada umumnya dialamioleh golongan pria paru baya dan golongan wanita yang sudah memasuki masa post- menupause. Penelitian ini bertujuan untuk menentukan prevalensi gout di Desa Kaweruan, dan menemukan pendasaran genetik dari kejadian gout di Desa Batu melalui familial studies.Pengambilan data dilakukan pada semua laki – laki berusia 18 tahun keatas dengan cara mengisi kuesioner dan wawancara pada anggota keluarga terkait untuk pasien gout. Analisis data menggunakan uji korelasi pearson, dan regresi di Desa Kaweruan, dan analisis pedigree untuk meneliti GA tophus di Desa Batu. Hasil penelitian menunjukan Desa Kaweruan dengan total 194 responden laki –laki berusia 18 – 84 tahun, memiliki prevalensi asam urat ≥ 7 mg/dl dimana terdapat 31 orang (15 %) pada rentang 7 – 9 mg/dl; dan 6 orang (5 %) > 9 mg/dl. Di desa Batu pun ditemukan adanya penderita GA Tophus yang dilihat pada analisis pedigree bahwa pada tingkat III terdapat tiga orang penderita GA, dua diantaranya terindikasi GA tophus. Namun belum bisa dibuktikan secara genetik bahwa GA tophus diturunkan dari tingkat I atau II dikarenakan tidak ada riwayat pemeriksaan kesehatan.
Gout Arthtitis (GA) is an inflammatory disease of the joints, especially in the joints due to the formation of monosodium urate (MSU) crystals in the tissues, which is generally experienced by elderly men and postmenopausal women. This study aims to determine the prevalence of gout in the village of Kaweruan, and to determine the genetic basis of the incidence of gout in the village of Batu through a familial study. Data was collected on all men aged 18 years and over by filling out questionnaires and interviews with family members about gout patients. Data analysis used Pearson correlation test, and regression in Kaweruan Village, and genealogical analysis to test tophus GA in Batu Village. The resultsshowed that Kaweruan Village with 194 male respondents aged 18 – 84 years, had a uric acid prevalence of 7 mg/dl where there were 31 people (15%) in the range of 7 – 9 mg/dl; and 6 people (5%) > 9 mg/dl. In Batu village there are three GA Tophus patients, which canbe seen in the genealogical analysis that at level III there are three GA patients, two of whomshow GA tophus. However, it has not been genetically proven that GA tophus is inherited from level I or II because there is no history of medical examinations.
URI: https://repository.uksw.edu/handle/123456789/22359
Appears in Collections:T1 - Nutrition Science

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